|
back to top
The repository maintains an up-to-date inventory system that
makes it possible to
keep a current balance of all stocks and to project
future needs. Of importance, comparable to that of the major goal of the
repository, is the task of ensuring the safe handling of these dangerous
materials at all steps in their processing. The equipment and handling
procedures used in this program have been selected to ensure the minimum hazard
to personnel and the environment, from synthesis, receipt at the repository, to
receipt by the user. All shipments are made in conformance with transportation
regulations.
Shipments made from the repository are sent by commercial air
freight.
Although most of the compounds stocked by the repository are
known
carcinogens, some are not. Many may still be controversial, at least in
regard
to their effect on humans. However, to stock both carcinogens and
noncarcinogens and to provide for different handling, packaging, and shipping
procedures for each, leaves many opportunities for error, leading to possible
exposure, mislabeling, mishandling, or accidental release of carcinogens to the
environment. Therefore, all compounds entrusted to the repository are regarded
as potential carcinogens and are handled, packaged, and labeled accordingly.
This is not necessarily meant to imply that the sample is a known
carcinogen--only that it is intended for use in research involving chemical
carcinogens, and unless the recipient has contrary information, the chemical
should be treated as a carcinogen with proper safety equipment and practices.
The repository provides data sheets for the compounds in
stock, which include
information concerning chemical and physical properties,
analytical data, hazards, storage, and handling.
back to top
The
Carcinogenesis Cancer Etiology Branch is eager to be made aware of
publications resulting from the use of chemicals it has supplied. In light of
budgetary restrictions, it is frequently necessary and appropriate for a program
to justify its existence. If you find this service useful, please take the extra
time to keep us informed of your published results. Please send reprints of
published work to the address below:
Ellen Zaika
National Cancer Institute
Division of
Cancer Biology
Cancer Etiology Branch
6130 Executive Blvd.
Room 5071,
MSC 7398
Bethesda, MD 20892-7398
Indicate in the Materials & Methods section of your
publications that "compounds were obtained from the National Cancer Institute
Chemical Carcinogen Reference Standard Repository."
back to top
The publication entitled Handbook of Analytical
and Spectral Data for Polycyclic Aromatic Hydrocarbons, Volume I, Benzo[a]pyrene
and its Metabolites is available through the NCI Repository. This
book contains data for over 50 benzo[a]pyrene metabolites: chemical and physical
property data; thin-layer and high performance liquid chromatography;
ultraviolet/visible, infrared, and proton and carbon-13 nuclear magnetic
resonance spectroscopy; mass spectrometry; and synthesis references.
For more information, call (816) 753-7600, extension 1510 or
1523, or email Ms. Alice Clark: aclark@mriresearch.org
This catalog is divided into two sections. Ordering
instructions are provided in the front of each section.
View the
Fall 2004 NCI Catalog
back to top
Section 1 lists over 1,000 unlabeled chemicals available from
the NCI Chemical Carcinogen Reference Standard Repository at MRI. These
chemicals are organized by chemical class, alphabetically, and by CAS number.
Some classes are specific
(e.g., benzo[a]pyrenes, benz[a]anthracenes), while
others are broad (e.g., aromatic amines, pharmaceuticals). Chemicals are
organized alphabetically within each class. A complete list of all the classes
and their location in the section are provided in the table of contents. An
alphabetical list and a CAS number list of chemicals are provided after the
chemical class list in Section 1.
Section 2 lists the labeled compounds available.
Prices
All prices listed in this catalog are in U.S. dollars and
include shipping and handling charges. Every effort will be made to give
reasonable notice of price changes, but the repository reserves the right to
change prices without notice. Prices listed do not include any government tax or
fee, and these are not listed on the invoice. The purchaser assumes
responsibility for any applicable tax.
International Shipments
The actual cost of shipping per order will be assessed for
shipment outside North America. Repository orders are shipped by Federal Express
and Airborne Express/DHL.
Rush Shipments
An additional charge of $50.00 per order will be added to any
rush shipment. Rush orders will be shipped the same day, if possible, or within
24 hours of receipt of the purchase order and required paperwork.
Vendor Designation
Purchase orders for labeled and unlabeled compounds should
designate Midwest Research Institute as the vendor/contractor for the source of
materials and origin of the resulting invoice as follows:
NCI Chemical Carcinogen Reference Standard
Repository
c/o Midwest Research Institute
425 Volker
Boulevard
Kansas City, Missouri 64110-2299
Chemical Unit Cost
Standard unit amounts have been designated for the chemicals
in our inventory.
For compounds where the unit amount specified is 5 mg or
less, a nominal weight
unit is intended, and will depend on the amount of
material available as well as the
difficulty in weighing small quantities.
Unless otherwise requested, orders for
intermediate quantities will be filled
with multiples of the standard package sizes.
Quotations for substantially
larger amounts of most compounds can be provided
upon request to Ellen
Zaika, National Cancer Institute, Carcinogenesis Cancer Etiology Branch. Email:
zaika@mail.nih.gov.
Payment
Terms are net 30 days from the date of invoice.
Make Checks Payable to "Midwest Research Institute,"
P.O. Box 803308, Kansas City, MO 64180-3308. Visa and Mastercard are accepted
(U.S. orders only).
Licensing and Registration
Compliance with the terms of institutional, state, and
national regulations for the
procurement of radioactive materials is the
responsibility of the purchaser. Users
of radioisotopes should familiarize
themselves with all applicable regulations.
In the United States, the use and possession of radioactive
materials are governed by regulations issued by the U.S. Nuclear Regulatory
Commission (NRC) and published in the Federal Register in Title 10,
Code of Federal Regulations, Part 30. United States federal regulations require
that a copy of a customer's license, together with all amendments, be on file at
the contractor's office (Midwest Research Institute, Kansas City, MO) before
shipment of radioactive material can be made.
Delivery
Every effort is made to ensure prompt processing and delivery
of orders; however, no responsibility is assumed for delay or nondelivery by the
carrier. Normal domestic delivery, for items in stock, is 4 to 10 days from
receipt of an order. In order to avoid storage under improper conditions
resulting from delays in transit, chemicals are not shipped Thursday through
Sunday.
Notice Regarding Usage, Toxicity, and
Hazards
The repository chemicals are offered for laboratory
EXPERIMENTAL USE ONLY. They are not for human food, drug,
cosmetic, or household use. All of the compounds will bear the warning "CHEMICAL
CARCINOGEN." This is not necessarily meant to imply that the sample is a known
carcinogen -- only that it is intended for use in research involving chemical
carcinogens, and unless the recipient has information to the contrary, it should
be treated as a carcinogen.
WE CANNOT BE CERTAIN OF YOUR APPLICATION OF THE
ENCLOSED CHEMICALS. CONSEQUENTLY, WE OFFER NO WARRANTIES REGARDING USE, NOR WILL
WE BE RESPONSIBLE FOR ANY LOSS RESULTING FROM USE OF THE CHEMICALS. HOWEVER, IF
THE CHEMICALS ARE PROVEN TO BE DEFECTIVE, THE PURCHASE PRICE WILL BE RETURNED TO
THE PURCHASER UPON PROOF OF PURCHASE. WE EXPRESSLY DISCLAIM ANY WARRANTIES OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE.
Limitation on Consequential Damages and
Indemnification
The purchaser's exclusive remedy with respect to chemicals
proved to NCI's
satisfaction to be defective or nonconforming shall be return
of such products
to NCI's contractor as provided herein and refund of the
purchase price. NCI
AND ITS CONTRACTORS HAVE NO OTHER OBLIGATIONS OR
LIABILITIES,
WHETHER ARISING OUT OF BREACH OF CONTRACT, WARRANTY, TORT
OR
OTHER THEORIES OF LAW, WITH RESPECT TO CHEMICALS ACQUIRED
FROM NCI.
In addition, NCI and its contractors specifically disclaim any liability
for
personal injury or property damages, lost profits or revenues, loss of use
of
products or any associated equipment, cost of substitute products,
facilities or
services, downtime, shut-down or slow-down costs, or for any
other economic
loss and claims of any third party. THE PURCHASER
SHALL INDEMNIFY NCI
AND ITS CONTRACTORS for all losses, damages, and
expenses (including
attorney's fees and other cost of defending any action)
that NCI or its contractors
may sustain or incur as a result of any claim by
the purchaser, its agents, officers, employees, successors, assigns, customers,
or other persons in connection with the use of the products furnished
hereunder.
Return Shipments
The repositories will NOT accept return
shipments unless prior permission has
been given by the respective repository
and the repository has provided shipping
instructions. It is our policy to be
fair and equitable. We will attempt to cooperate
with the purchaser, but the
circumstances involving returns are often complicated
and unique to
individual purchasers which require individual attention and
specific
handling. Unidentified returned shipments may be discarded in light
of our quality
control standards. In the event that a complaint relating to
the quality of a product
is deemed by us to be valid and justifiable, then,
at our option, we will either replace the quantity free of charge or issue a
credit for the quantity in question. We want you to be satisfied with these
compounds and to have confidence in them. We include an analytical data sheet
with each order to inform you of the estimated purity and a material safety data
sheet to advise you of special handling precautions. If you encounter specific
problems with any of our compounds, please let us know. We will be happy to
provide technical assistance and information with respect to synthesis
techniques, or usable processes, solvents, and analytical techniques. In
general, the user should consider all of the repository compounds as sensitive
to light (particularly short wave ultraviolet), heat, and oxidizing agents.
back to top | 